2016 Archived Content

HealthcareBiological & Chemical Sensors for Healthcare Applications
December 5-6, 2016


Low cost materials and advances in nano and micro fabrication techniques within the manufacturing process have led to significant increases in the commercialization of biological and chemical sensors for healthcare applications. The increases in demand for diagnostics and measuring devices such as glucose monitoring, pacemakers and other implantables and wearables has helped to create a significant marketplace for this commercialization. This conference track will examine the latest advancements in research, development and engineering and will provide attendees with the state- of-the-art in biosensors development for healthcare.

Final Agenda

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Monday, December 5, 2016

8:00 am Conference Registration and Morning Coffee

8:55 Chairperson’s Opening Remarks

Kalle Levon, Ph.D., Research Professor, Chemical and Biomolecular Engineering Department, New York University


OPENING KEYNOTE PRESENTATIONS

9:00 The Intelligent Home, Medical Sensors – Nudging towards Better Health and Healthcare

Nick van TerheydenNick van Terheyden, M.D., CMO, Dell

This presentation will discuss the cultural, market and regulatory forces that are driving change, and how we are actively enhancing development, implementation and adopting novel technologies, services, and applications that will revolutionize information-driven care, that results in improved patient outcomes and overall cost savings worldwide.

9:30 Artificial Intelligence in Behavioral Health

Chris PoulinChris Poulin, Data Solution Architect, Microsoft

The Durkheim Project was a DARPA sponsored behavioral analytics project running from 2011-2015. In this talk, we will discuss the data collection methods, the machine learning algorithms, and the health related intelligence resulting from the system. Implications for current and future work in the field will also be discussed.


Sensors Roadmap for Healthcare

10:00 Sensing is the Future of Health Care: Technology Road Mapping Helps Find the Way

Noa Ghersin, Analyst, Lux Research

Wireless communication standards have evolved to allow sensors on or around patients to securely transmit data, greatly improving patient mobility and sensor utility. At the same time, significant increases in computing power are enabling automatic analysis of sensor data, while the advent of networking and cloud computing allows users to store and access data from almost anywhere. Understanding which technologies to develop and how to position them in the right market segments is paramount to success for companies looking to capitalize on the future growth.

10:30 Coffee Break with Exhibit & Poster Viewing


Advanced Materials, Design & Modeling for Biosensors

11:00 Organic Semiconductor Coatings on Floating and Extended Gate FETs for Disease Detection

Kalle Levon, Ph.D., Research Professor, Chemical and Biomolecular Engineering Department, New York University

Organic semiconductors provide excellent surfaces for biomolecular binding analyses because the conjugation of ligands is easy with the organic molecules, the surface area can be maximized with nano structures and the band gap control offers additional electronic amplification. We shall present effective gas analysis based on acid/base reactions and counter ion interactions and also results from monitoring enzymatic reaction utilizing the redox reaction on the surface.

11:30 Transdermal Microneedle Sensors to Measure Biomarker Signatures

Ronen Polsky, Ph.D., Principal Member of Technical Staff, Department of Physical, Biological, and Chemical Microsensors, Sandia National Laboratories

The realization of a microneedle transdermal diagnostic platform has a wide range of applications including sports medicine, medical triage scenarios, and point-of-care diagnostics. I will describe work that (1) explores what needle geometries are best suited to penetrate the dermis and extract interstitial fluid (IF) with minimal discomfort, (2) identify select biomarkers that are accessible in IF and understand how interstitial levels correlate with clinically-relevant blood/plasma levels, and (3) design integrated sensor transducers that can detect biomarkers from extracted IF.


Regulatory Challenges to Commercialization

12:00 pm Regulatory Considerations for Commercialization of Medical Devices

Orlando Lopez, Ph.D., Biomedical Engineer, Lead Regulatory Reviewer, Office of Device Evaluation, FDA

Discussion of the FDA regulatory process and associated considerations for taking a new medical device to market. Specific emphasis will be given to performance testing considerations needed to demonstrate safety and effectiveness of sensor-based devices.

12:30 Luncheon Presentation (Sponsorship Opportunity Available) or Enjoy Lunch on Your Own


Next Generation Wearables

1:55 Chairperson’s Remarks

Nick van Terheyden, M.D., CMO, Dell

2:00 Healthcare Applications of Wearable Sensors & Systems and Wearable Patient Monitoring for Low Acuity Hospital Settings, Challenges and Opportunities

Rasoul Yousefi, Ph.D., Algorithms|Technology Development, RMS - Patient Monitoring & Recovery – MITG, Medtronic

Wearable monitoring is going beyond consumer electronics, and hospitals around the world are adopting wearable devices to reduce overall cost of care delivery. In this talk, I will review opportunities for outcome-driven wearable monitoring of patients in the general care floor with respect to the value-based healthcare system. Technical Challenges in research and development of wearable monitoring solutions will be discussed and state-of-the-art solutions and future trends will be presented.

2:30 Wearable Sensor Technologies: Their Future in Patient / Clinician Decision Making

Christopher M. Hartshorn, Ph.D., Program Manager, Office of Cancer Nanotechnology Research, National Cancer Institute

Wearable technologies for the consumer market have recently seen widespread adoption with a massive increase in sales of more than 180% in 2015. These wearable devices are designed to measure multiple human performance-based metrics via built-in and/or external sensors, continuously. This talk will focus on several large scale initiatives at the National Institutes of Health and attempt to chart the path forward relative to these questions.

3:00 Sponsored Presentation (Opportunity Available)

3:30 Refreshment Break with Exhibit & Poster Viewing

4:00 Wearable Transdermal Biosensors: Understanding the Chemical Self

Joshua Windmiller, Ph.D., CTO & Founder, Biolinq Technologies, Inc.

This talk highlights the development of a novel class of minimally-invasive electrochemical biosensors that facilitate the quantification of relevant metabolomic, electrolytic, hormonal, and neurochemical information in a continuous, real-time fashion. Fabricated through manufacturing processes that are scalable, cost-effective, and have a minimum environmental footprint, these novel biosensing modalities seek to bridge the gap between analytical-grade instrumentation typically found in the hospital laboratory and user requirements for unobtrusive, low-profile, skin-applied devices able to deliver timely, clinically-accurate, and actionable information using existing wirelessly-enabled wearable and mobile platforms.

4:30 Wearable Biosensors for Longitudinal Monitoring

Shekhar Bhansali, Ph.D., Alcatel-Lucent Professor & Chair, Electrical and Computer Engineering Department, Florida International University

Recent advances in sensing technologies are enabling a new class of wearable sensors that can continuously monitor both physiology and biochemistry of the patient in their native environment unobtrusively. This talk shares the recent developments in wearable sensing technologies, with an emphasis on wearable biosensing technologies, and introduces various use cases where these technologies can disruptively change health outcomes.

5:00 Welcome Reception with Exhibit & Poster Viewing

6:00 End of Day & Tutorial Registration

6:30-8:30 Tutorial: Sensor Data Management*

*Separate registration required.

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Tuesday, December 6, 2016

8:00 am Morning Coffee

8:25 Chairperson’s Opening Remarks

Christopher M. Hartshorn, Ph.D., Program Manager, Office of Cancer Nanotechnology Research, National Cancer Institute


KEYNOTE PRESENTATION

8:30 Securing the New Wearables World

Gary DavisGary Davis, Chief Consumer Security Evangelist, Intel Security

Wearables are opening up new pathways that facilitate the tracking, sharing and storing of consumers’ personal health, location and daily activity data. Someone’s heart rate, blood pressure, finances, demographics and daily routine, including exercise habits and commuting patterns, are being collected and used to improve everyday life. By effectively addressing the security vulnerabilities, privacy concerns and regulation issues that come with the evolving wearable industry, this brave new world can be enjoyed by all.

9:00 A Wearable Biochemical Sensor for Monitoring Alcohol ConsumptionThrough Metabolite Detection in Sweat

Anjan Panneer Selvam, Ph.D., Research Scientist, Adjunct Professor, Texas Biomedical Device Center, Department of BioEngineering, University of Texas and Dallas


Applications and Market

9:30 The Fusion of Wearable Sensors and Medical Diagnostics: Tools vs. Toys

Baabi Das, President & Co-Founder, Zansors

10:00 Coffee Break with Exhibit & Poster Viewing

10:45 Waterborne Pathogen Detection Using a Smartphone-Based Fluorescence Microscope and Machine Learning

Hatice Ceylan Koydemir, Ph.D., Postdoctoral Researcher, Electrical Engineering, UCLA

Giardia lamblia is a waterborne parasite that causes an intestinal infection, known as giardiasis, and it is found not only in countries with inadequate sanitation and unsafe water but also streams and lakes of developed countries. Here we present a cost-effective and field portable mobile-phone based fluorescence microscopy platform that is well beyond of technology readiness level of 5.

11:15 Mobile Spions: Composite Micro Particles for Local Sensing

Michael Koehler, Ph.D., Professor, Physical Chemistry and Microreaction Technology, Technical University, Ilmenau, Germany

Special architectures of composite micro and nanoparticles are usable as miniaturized mobile sensors. They can be applied as "spion-like" transducers in tissues, cells and microfluidic compartments. New technologies allow the generation of these composed particles with very high homogeneity. The lecture will introduce the concept and will give examples for synthesis of sensor particles and their application in chemistry, for monitoring of cell cultures and toxicity studies.

11:45 pm A Colorimetric Microplate Reader for Point-of-Care ELISA Quantification

Qingshan Wei, Ph.D., Postdoctoral Scholar, Bioengineering Department, Electrical Engineering Department, University of California, Los Angeles

We developed a cost-effective and handheld smartphone-based colorimetric microplate reader for rapid digitization and quantification of immunoserology-related ELISA tests in a conventional 96-well plate format. Using this post-of-care (POC) testing platform, we quantified four different FDA-approved ELISA tests (mumps IgG, measles IgG, and herpes simplex virus IgG (HSV-1 and HSV-2)) in a clinical microbiology lab using 1138 remnant patient samples (roughly 50% training and 50% testing), and achieved >~99% accuracy for each ELISA test.

12:15 Luncheon Presentation (Sponsorship Opportunity Available) or Enjoy Lunch on Your Own

1:00 Close of Biological and Chemical Sensors for Healthcare Applications



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For more details on the meeting, please contact the conference organizing committee:
Craig Wohlers
Executive Director, Conferences
Knowledge Foundation, a division of Cambridge Innovation Institute
Phone: (+1) 781-972-6260
Email: cwohlers@knowledgefoundation.com

For partnering and sponsorship information, please contact:
Sherry Johnson
Business Development Manager
Knowledge Foundation
Phone: (+1) 781-972-1359
Email: sjohnson@healthtech.com

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